1-[3-(Chloromethyl)phenyl]imidazole synthesis
- Product Name:1-[3-(Chloromethyl)phenyl]imidazole
- CAS Number:129747-33-7
- Molecular formula:C10H9ClN2
- Molecular Weight:192.64
57455-06-8
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Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: potassium fluoride; potassium carbonate / copper / N,N-dimethyl-formamide / 6 h / 175 °C
2.1: thionyl chloride / N,N-dimethyl-formamide / 40 h / 20 °C
2.2: pH 9 - 10
References:
N.V. ORGANON WO2006/100208, 2006, A1
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