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1-[4-(difluoromethoxy)phenyl]propan-1-amine synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 42 percent / K2CO3 / dimethylformamide / 3 h / 100 °C
2: 20 percent / H2; NH3; Al(OH)3 / Raney nickel / methanol / 7 h / 100 °C / 14710.2 Torr

References:

Yamanaka;Moritomo;Fujii;Tanaka;Fukuda;Nishimura [Pesticide Science,1998,vol. 54,# 3,p. 223 - 229]