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ChemicalBook CAS DataBase List 1-Benzyl-1H-pyrazol-5-ol

1-Benzyl-1H-pyrazol-5-ol synthesis

2synthesis methods
651755-15-6 Synthesis
1H-Pyrazole-4-carboxylic acid, 5-hydroxy-1-(phenylmethyl)-, ethyl ester

651755-15-6
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Yield:33641-17-7 59%

Reaction Conditions:

Stage #1: ethyl 1-benzyl-5-hydroxy-1H-pyrazole-4-carboxylatewith potassium hydroxide in methanol; for 24 h;Heating;
Stage #2: with hydrogenchloride pH=2; for 12 h;Heating;

References:

Holzer, Wolfgang;Krca, Ingrid [Heterocycles,2003,vol. 60,# 10,p. 2323 - 2342]