1-BENZYL-3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE synthesis

5synthesis methods

Product Name:1-BENZYL-3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE
CAS Number:127234-68-8
Molecular formula:C20H19NO2
Molecular Weight:305.37

61160-18-7 Synthesis

61160-18-7
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100-39-0
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$10.00/10g

584-08-7 Synthesis

584-08-7
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$5.00/100g

1-BENZYL-3-(BENZYLOXY)-2-METHYL-4(1H)-PYRIDINONE

127234-68-8
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Yield:127234-68-8 70%

Reaction Conditions:

in ethanol;Petroleum ether;

Steps:

3.a 1-(phenylmethyl)-2-methyl-3-(phenylmethoxy) 4-pyridone

EXAMPLE 3a 1-(phenylmethyl)-2-methyl-3-(phenylmethoxy) 4-pyridone 73 g of the product of Example 2 were dissolved in 4 liters of ethanol (dry). 25 g K₂ CO₃ powderized and 70 g benzylbromide were added. After refluxing for 4 hours and filtration, the solvent was distilled off and the residue extracted with 4 liters of hot petroleum ether in 3 parts. After cooling to room temperature and filtration the petroleum ether filtrate was concentrated to 2 liters and cooled to -10° C. 31 g of white crystals of the title compound of Example 3 were obtained. The formed title compound 3A was insoluble in petroleum ether at room temperature white crystals. 70% of total yield.

References:

US5112968,1992,A

61160-18-7 Synthesis

61160-18-7
75 suppliers
$28.00/250mg

100-44-7 Synthesis