1-DECANESULFONYL CHLORIDE synthesis
- Product Name:1-DECANESULFONYL CHLORIDE
- CAS Number:61652-81-1
- Molecular formula:C10H21ClO2S
- Molecular Weight:240.79
10496-18-1
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$8.00/1g
61652-81-1
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$96.00/10g
Yield: 91%
Reaction Conditions:
with N-chloro-succinimide in water;acetonitrile at 20; for 1 h;
Steps:
Representative experimental procedure to prepare sulfonylchloride from disulfides
General procedure: To a stirred solution of p-tolyl disulfide ( 1b) (246.3mg, 1.0mmol) in acetonitrile (2.0mL) and water (0.2mL), N-chlorosuccinimide (802mg, 6.0mmol) was added, and the resulting mixture was stirred at room temperature for 3h. Water (10mL) was added and the resulting mixture was extracted with ethyl acetate (20mL×3). The extract was washed with brine, dried over anhydrous magnesium sulfate, and evaporated. Chromatography on silica gel using n-hexane/ethyl acetate as the eluent gave the sulfonyl chloride ( 4b) (304.7mg, 83%) as colorless crystals.
References:
Kirihara, Masayuki;Naito, Sayuri;Nishimura, Yuki;Ishizuka, Yuki;Iwai, Toshiaki;Takeuchi, Haruka;Ogata, Tomomi;Hanai, Honoka;Kinoshita, Yukari;Kishida, Mari;Yamazaki, Kento;Noguchi, Takuya;Yamashoji, Shiro [Tetrahedron,2014,vol. 70,# 14,p. 2464 - 2471]
112-29-8
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$6.00/25g
61652-81-1
21 suppliers
$96.00/10g
5349-20-2
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$144.00/250mg
61652-81-1
21 suppliers
$96.00/10g