![](/CAS/GIF/65313-46-4.gif)
1-Hydroxyhexane-2,5-dione synthesis
- Product Name:1-Hydroxyhexane-2,5-dione
- CAS Number:65313-46-4
- Molecular formula:C6H10O3
- Molecular Weight:130.14
![5-Hydroxymethylfurfural](/CAS/GIF/67-47-0.gif)
67-47-0
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$5.00/100mg
![1-Hydroxyhexane-2,5-dione](/CAS/GIF/65313-46-4.gif)
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Yield:65313-46-4 93.3%
Reaction Conditions:
with formic acid;C34H50Ir2N4O6(4+)*2O4S(2-);sodium formate at 130; pH=2.5; for 2 h;Reagent/catalyst;Temperature;pH-value;
Steps:
11
Weigh 1mmol5-HMF (126mg), using 1mol / L of formic acid 5mlpH = 2 / dissolving sodium formate buffer solution and transferred to a 35mL glass pressure tube was added 200μL 2 catalyst (catalyst concentration: [Cp * Ir- (di-R -bpy) (OH2)] SO4Complexes 0.50mmol / L), i.e. 100ppm (when compared to a dual site catalyst Ir 50ppm) catalyst, with magnetic stirring and the reaction was heated in an oil bath 120 2H; After completion of the reaction, ice-water bath and cool to room temperature.The 5-HMF feedstock quality similar dimethyl phthalate internal standard added to the reaction mixture, washed with methanol and 20ml wall.After the mixed reaction liquid to take appropriate centrifuge tube, with a larger volume of the reaction solution was taken in methanol and then diluted into after centrifugation centrifuge.Gas chromatography (GC (2104, Shimazu, FID) fitted on the DM-WAX (30m × 0.32mm × 0.25μm) for detecting the column combination in gasifier temperature setting 250 , detector temperature setting 280 , column oven temperature setting 180 holding 20min. linear velocity of 45cm / s, split ratio was 50.) reacting a compound of quantitative detection system, measured HHD yield was 36.2%Specific reaction and detecting the same manner as in Example 1, except that the catalyst was changed to the catalyst 8, formic acid / sodium formate buffer solution adjusted to pH 2.5, the reaction temperature was 130 .The resulting product is 1-hydroxy-2,5-dione (the HHD) in a yield of 93.2%
References:
CN105712854,2016,A Location in patent:Paragraph 0074; 0075
![5-Hydroxymethylfurfural](/CAS/GIF/67-47-0.gif)
67-47-0
582 suppliers
$5.00/100mg
![2,5-Furandimethanol](/CAS/GIF/1883-75-6.gif)
1883-75-6
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$8.00/250mg
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![2,5-Hexanedione](/CAS/GIF/110-13-4.gif)
110-13-4
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$10.00/5g
![2,5-Furandimethanol](/CAS/GIF/1883-75-6.gif)
1883-75-6
272 suppliers
$8.00/250mg
![1-Hydroxyhexane-2,5-dione](/CAS/GIF/65313-46-4.gif)
65313-46-4
2 suppliers
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