1-Methoxy-2-naphthalenamine synthesis

5synthesis methods

Product Name:1-Methoxy-2-naphthalenamine
CAS Number:3178-03-8
Molecular formula:C11H11NO
Molecular Weight:173.21

4900-62-3
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3178-03-8
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Yield:3178-03-8 94.1%

Reaction Conditions:

with hydrogen in methanol at 20;

Steps:

1-methoxy-2-naphthylamine (2i).

General procedure: A mixture of 2-methoxy-1-nitronaphthalene (340 mg,1.67 mmol) dissolved in MeOH (10 ml) and Raney Nickel (80 mg) was stirred at ambientNO2HONO2MeONH2MeOME2SO4 / K2CO3CH3CNreflux / 1 hReney nickel / H2 gasMeOHr.t. / 1 h7 8 2atemperature under hydrogen balloon for 4 hrs.

References:

Oh, Soo-Jin;Hwang, Seok Jin;Jung, Jonghoon;Yu, Kuai;Kim, Jeongyeon;Choi, Jung Yoon;Hartzell, H. Criss;Roh, Eun Joo;Justin Lee [Molecular Pharmacology,2013,vol. 84,# 5,p. 726 - 735] Location in patent:supporting information

Diazene, 1-(1-methoxy-2-naphthalenyl)-2-phenyl-

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References

607-24-9 Synthesis

607-24-9
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$9.00/1g

3178-03-8
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80409-51-4
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