1-METHYL-3-CYCLOHEXENECARBOXYLICACID synthesis
- Product Name:1-METHYL-3-CYCLOHEXENECARBOXYLICACID
- CAS Number:16646-42-7
- Molecular formula:C8H12O2
- Molecular Weight:140.18
4771-80-6
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$5.00/10g
74-88-4
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16646-42-7
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$503.81/5MG
Yield:16646-42-7 97%
Reaction Conditions:
Stage #1: 1,2,5,6-tetrahydrobenzoic acidwith n-butyllithium;bis(dimethylamino)(i-propyl)phosphine oxide;diisopropylamine in tetrahydrofuran;hexane at -20 - 20;Inert atmosphere;
Stage #2: methyl iodide in tetrahydrofuran;hexane at -25 - 20;
References:
Hosoya, Masahiro;Otani, Yuko;Kawahata, Masatoshi;Yamaguchi, Kentaro;Ohwada, Tomohiko [Journal of the American Chemical Society,2010,vol. 132,# 42,p. 14780 - 14789] Location in patent:supporting information; experimental part
6493-80-7
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16646-42-7
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$503.81/5MG
4771-80-6
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$5.00/10g
108-18-9
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$10.00/1g
74-88-4
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$15.00/10g
16646-42-7
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$503.81/5MG
79-41-4
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$14.00/5g
106-99-0
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$82.00/100mL
16646-42-7
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$503.81/5MG
931-96-4
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16646-42-7
50 suppliers
$503.81/5MG