1-METHYL-5-NITRO-1H-PYRAZOLE-4-CARBOXYLIC ACID synthesis

1synthesis methods

Product Name:1-METHYL-5-NITRO-1H-PYRAZOLE-4-CARBOXYLIC ACID
CAS Number:18213-77-9
Molecular formula:C5H5N3O4
Molecular Weight:171.11

1H-Pyrazole-4-carboxylicacid,5-amino-1-methyl-(9CI)

4058-91-7
120 suppliers
$21.00/1g

1-METHYL-5-NITRO-1H-PYRAZOLE-4-CARBOXYLIC ACID

18213-77-9
42 suppliers
$116.64/1gm:

Yield:-

Reaction Conditions:

Stage #1: 5-amino-1-methyl-1H-pyrazole-4-carboxylic acidwith tetrafluoroboric acid;sodium nitrite in water;
Stage #2: with copper;sodium nitrite

References:

Dounay, Amy B.;Anderson, Marie;Bechle, Bruce M.;Evrard, Edelweiss;Gan, Xinmin;Kim, Ji-Young;McAllister, Laura A.;Pandit, Jayvardhan;Rong, Suobao;Salafia, Michelle A.;Tuttle, Jamison B.;Zawadzke, Laura E.;Verhoest, Patrick R. [Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,# 7,p. 1961 - 1966]

1-METHYL-5-NITRO-1H-PYRAZOLE-4-CARBOXYLIC ACID Related Search:

1H-Pyrazole-4-carboxaldehyde (1H-PYRAZOL-4-YL)METHANOL (1-Methyl-1H-pyrazol-4-yl)methanol 1-Methyl-1H-pyrazole-4-carbaldehyde 4-Pyrazolecarboxylic acid 3-Nitro-1H-pyrazole 1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 3-Aminopyrazole-4-carboxylic acid 5-Amino-1-methyl-1H-pyrazole-4-carbaldehyde 4-METHYL-1H-PYRAZOL-3-AMINE