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1-METHYLTHYMINE synthesis

8synthesis methods
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Yield:4160-72-9 85%

Reaction Conditions:

Stage #1: thyminwith sulfuric acid;1,1,1,3,3,3-hexamethyl-disilazane in toluene;
Stage #2: methyl iodide in N,N-dimethyl-formamide;toluene;

References:

Strobykina, Irina Yu.;Andreeva, Olga V.;Belenok, Mayya G.;Semenova, Marina N.;Semenov, Victor V.;Chuprov-Netochin, Roman N.;Sapunova, Anastasiya S.;Voloshina, Alexandra D.;Dobrynin, Alexey B.;Semenov, Vyacheslav E.;Kataev, Vladimir E. [Medicinal Chemistry Research,2020,vol. 29,# 12,p. 2203 - 2217]

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