1-METHYLTRYPTAMINE synthesis
- Product Name:1-METHYLTRYPTAMINE
- CAS Number:7518-21-0
- Molecular formula:C11H14N2
- Molecular Weight:174.24
![Carbamic acid, N-[2-(1-methyl-1H-indol-3-yl)ethyl]-, 1,1-dimethylethyl ester](/CAS/20210111/GIF/919787-22-7.gif)
919787-22-7
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7518-21-0
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$185.00/200 mg
Yield: 85%
Reaction Conditions:
with trifluoroacetic acid in dichloromethane at 0 - 20; for 1 h;Concentration;
Steps:
30.C C. 2-(1-Methyl-1H-indol-3-yl)ethanamineC.
C.
2-(1-Methyl-1H-indol-3-yl)ethanamine
To a solution of tert-butyl (2-(1-methyl-1H-indol-3-yl)ethyl)carbamate (1.29 g, 4.71 mmol) in DCM (15 mL) was added TFA (7 mL) at ˜0° C. to 5° C.
The resulting reaction mixture was stirred at room temperature for 1 h.
The reaction mixture was concentrated to give the crude product which was diluted with DCM and washed with sodium bicarbonate aqueous solution.
The organic layer was washed with brine, dried and concentrated to give the desired product (700 mg, 4.02 mmol, 85% yield) as yellow oil. MS (ESI) m/z 175.1 [M+H]+.
References:
Location in patent:Paragraph 0405
61-54-1
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74-88-4
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7518-21-0
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$185.00/200 mg
110-88-3
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61-54-1
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$12.00/5 g
7518-21-0
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$185.00/200 mg
61-54-1
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373-68-2
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7518-21-0
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103549-24-2
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7518-21-0
43 suppliers
$185.00/200 mg