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1-phenylpiperidine-2,6-dione synthesis

12synthesis methods
-

Yield:5768-13-8 87%

Reaction Conditions:

Stage #1: 1,5-pentanedioic acidwith thionyl chloride for 0.5 h;Reflux;
Stage #2: aniline in benzene;Reflux;

References:

Rajput;Girase [Indian Journal of Heterocyclic Chemistry,2012,vol. 21,# 3,p. 201 - 208]