1-Tert-butyl-3-broMo-5-fluorobenzene synthesis
- Product Name:1-Tert-butyl-3-broMo-5-fluorobenzene
- CAS Number:1123172-38-2
- Molecular formula:C10H12BrF
- Molecular Weight:231.1
98-54-4
403 suppliers
$15.00/25g
1123172-38-2
42 suppliers
$122.00/100mg
Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: bromine / dichloromethane / 4.17 h / 0 - 20 °C
2.1: triethylamine / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
3.1: n-butyllithium / hexane; diethyl ether / 1 h / -78 °C / Inert atmosphere
3.2: 4 h / -78 °C / Inert atmosphere
4.1: tetrabutylammonium tetra(tert-butyl alcohol) coordinate fluoride / tetrahydrofuran / 0 h / 20 °C / Inert atmosphere; Flow reactor
References:
Ikawa, Takashi;Masuda, Shigeaki;Akai, Shuji [Chemical and Pharmaceutical Bulletin,2018,vol. 66,# 12,p. 1153 - 1164]
1123173-10-3
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$13.00/100mg
1123172-38-2
42 suppliers
$122.00/100mg
1644527-00-3
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inquiry
1123172-38-2
42 suppliers
$122.00/100mg
3972-64-3
147 suppliers
$9.00/1g
1123172-38-2
42 suppliers
$122.00/100mg
98-22-6
67 suppliers
$45.00/50mg
1123172-38-2
42 suppliers
$122.00/100mg