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Spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic acid, α-ethyl-6'-formyl-2',3'-dihydro-5'-oxo-, ethyl ester synthesis

1synthesis methods
58610-66-5 Synthesis
Spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic acid, 6'-cyano-α-ethyl-2',3'-dihydro-5'-oxo-, ethyl ester

58610-66-5
10 suppliers
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Spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic acid, α-ethyl-6'-formyl-2',3'-dihydro-5'-oxo-, ethyl ester

1010803-94-7
2 suppliers
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Yield:1010803-94-7 60%

Reaction Conditions:

with water;hydrogen;nickel in pyridine;acetic acid at 50; under 760.051 Torr; for 6 h;

References:

Zhang, Li-Peng;Baoa, Yong;Kuang, Yun-Yan;Chen, Fen-Er [Helvetica Chimica Acta,2008,vol. 91,# 11,p. 2057 - 2061] Location in patent:experimental part