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ChemicalBook CAS DataBase List tert-butyl 4-(1H-indol-5-yl)piperidine-1-carboxylate
1049677-53-3

tert-butyl 4-(1H-indol-5-yl)piperidine-1-carboxylate synthesis

3synthesis methods
10075-50-0 Synthesis
5-Bromoindole

10075-50-0
689 suppliers
$5.00/10g

1048970-17-7 Synthesis
tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

1048970-17-7
150 suppliers
$11.00/250mg

tert-butyl 4-(1H-indol-5-yl)piperidine-1-carboxylate

1049677-53-3
12 suppliers
inquiry

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Yield:1049677-53-3 75%

Reaction Conditions:

with morpholine;nickel(II) chloride ethylene glycol dimethyl ether complex;[4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-κN1,κN1′]bis[3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC]iridium hexafluorophosphate;4,4′-di-tert-butyl-2,2′-bipyridine in N,N-dimethyl-formamide at 20; for 2 h;Irradiation;

References:

Speckmeier, Elisabeth;Maier, Thomas C. [Journal of the American Chemical Society,2022,vol. 144,# 22,p. 9997 - 10005] Location in patent:supporting information

10075-50-0 Synthesis
5-Bromoindole

10075-50-0
689 suppliers
$5.00/10g

180695-79-8 Synthesis
1-N-BOC-4-BROMOPIPERIDINE

180695-79-8
196 suppliers
$14.00/1g

tert-butyl 4-(1H-indol-5-yl)piperidine-1-carboxylate

1049677-53-3
12 suppliers
inquiry