4-(Chloromethyl)-5-methyl-1-(triphenylmethyl)-1H-imidazole synthesis
- Product Name:4-(Chloromethyl)-5-methyl-1-(triphenylmethyl)-1H-imidazole
- CAS Number:106147-85-7
- Molecular formula:C24H21ClN2
- Molecular Weight:372.89
106147-84-6
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$80.00/1g
106147-85-7
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$45.00/100mg
Yield:-
Reaction Conditions:
with thionyl chloride;triethylamine in benzene;
Steps:
1.b b.
b. Synthesis of 1-trityl-4-chloromethyl-5-methylimidazole 3. 0.41 ml of thionyl chloride are added drop by drop to a solution of 2 g of 1-trityl-4-hydroxymethyl-5-methylimidazole 2 and 0.83 ml of triethylamine in 28 ml of anhydrous benzene. After 45 minutes of stirring at room temperature the solution is filtered and the precipitate is washed with benzene. The combined organic phases are dried over calcium chloride and evaporated under reduced pressure. Thus 1-trityl-4-chloromethyl-5-methylimidazole 3 is obtained in the form of a yellow solid which is immediately used in the following step.
References:
US4738979,1988,A
76-83-5
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106147-85-7
31 suppliers
$45.00/100mg
29636-87-1
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$30.05/5G
106147-85-7
31 suppliers
$45.00/100mg