ChemicalBook
CAS DataBase List
Ethyl 2-phenyl-4-(2,2,2-trifluoroethyl)-4,5-dihydrooxazole-4-carboxylate
![](/CAS/GIF/1126530-82-2.gif)
Ethyl 2-phenyl-4-(2,2,2-trifluoroethyl)-4,5-dihydrooxazole-4-carboxylate synthesis
1synthesis methods
- Product Name:Ethyl 2-phenyl-4-(2,2,2-trifluoroethyl)-4,5-dihydrooxazole-4-carboxylate
- CAS Number:1126530-82-2
- Molecular formula:C14H14F3NO3
- Molecular Weight:301.26
Yield:1126530-82-2 31%
Reaction Conditions:
Stage #1: trimethylsulfoxonium iodidewith sodium hydride in dimethyl sulfoxide;mineral oil at 20; for 0.5 h;
Stage #2: (Z)-ethyl 2-benzamido-4,4,4-trifluorobut-2-enoate in dimethyl sulfoxide;mineral oil at 20; for 72 h;
References:
Wan, Wen;Gao, Yinghong;Jiang, Haizhen;Hao, Jian [Journal of Fluorine Chemistry,2008,vol. 129,# 6,p. 510 - 514] Location in patent:experimental part