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N2,N3,N4-TRIS-(TERT-BUTYLOXYCARBONYL)-1,5,10,14-TETRA-AZA-QUATRODECANE synthesis

14synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: methanol / 24 h
2: 87 percent / H2; aq. NaOH / Raney-Ni / ethanol; tetrahydrofuran / 7 h / 20 °C
3: 36 percent / tetrahydrofuran / 4 h

References:

Bueno, G. Jimenez;Klimkait;Gilbert;Simons [Bioorganic and Medicinal Chemistry,2003,vol. 11,# 1,p. 87 - 94]

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