![](/CAS/GIF/1196507-56-8.gif)
1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)- synthesis
- Product Name:1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)-
- CAS Number:1196507-56-8
- Molecular formula:C13H8ClIN2O2S
- Molecular Weight:418.64
![4-CHLORO-5-IODO-1H-PYRROLO[2,3-B]PYRIDINE](/CAS2/GIF/1015610-31-7.gif)
1015610-31-7
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$42.00/250mg
![Benzenesulfonyl chloride](/CAS/GIF/98-09-9.gif)
98-09-9
338 suppliers
$12.00/25g
![1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)-](/CAS/GIF/1196507-56-8.gif)
1196507-56-8
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Yield:1196507-56-8 98%
Reaction Conditions:
Stage #1: 4-chloro-5-iodo-1H-pyrrolo[2,3-b]pyridinewith sodium hydride in N,N-dimethyl-formamide;mineral oil at 0; for 0.333333 h;
Stage #2: benzenesulfonyl chloride in N,N-dimethyl-formamide;mineral oil at 20; for 2 h;
Steps:
12.C
[00335] Step C: NaH (0.960 g, 24.0 mmol, 60% dispersion in mineral oil) at 00C was added to 4-chloro-5-iodo-lH-pyrrolo[2,3-b]pyridine (5.57 g, 20.0 mmol) in dimethylformamide ("DMF"; 40 mL) and stirred at 00C for 20 minutes. Benzenesulfonyl chloride (2.82 mL, 22.0 mmol) was added, and the reaction was stirred at room temperature for 2 hours. Water (200 mL) was added and stirred for 10 minutes. The solid formed was collected by filtration, washed with
References:
WO2009/140320,2009,A1 Location in patent:Page/Page column 98-99
![1H-Pyrrolo[2,3-b]pyridine, 4-chloro-1-[tris(1-methylethyl)silyl]-](/CAS/GIF/651744-48-8.gif)
651744-48-8
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$225.00/1g
![1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)-](/CAS/GIF/1196507-56-8.gif)
1196507-56-8
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![4-CHLORO-5-IODO-1-(TRIISOPROPYLSILYL)-1H-PYRROLO[2,3-B]PYRIDINE](/CAS/GIF/1015609-83-2.gif)
1015609-83-2
15 suppliers
$155.00/50mg
![1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)-](/CAS/GIF/1196507-56-8.gif)
1196507-56-8
10 suppliers
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