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5-(2-phenyl-1,3-thiazol-4-yl)-1,3,4-oxadiazol-2-amine synthesis

3synthesis methods
-

Yield:1219827-72-1 70%

Reaction Conditions:

Stage #1: 2-phenyl-1,3-thiazole-4-carboxylic acid hydrazidewith water;sodium hydrogencarbonate in 1,4-dioxane at 20; for 0.0833333 h;
Stage #2: bromocyane in 1,4-dioxane at 20;

References:

Thore;Gupta, Sunil V.;Baheti, Kamalkishor G. [Medicinal Chemistry Research,2013,vol. 22,# 8,p. 3802 - 3811]