![](/CAS/20180703/GIF/1237261-60-7.gif)
(1S,2R)-2-(chloromethyl)-N,N-diethyl-1- phenylcyclopropanecarboxamide synthesis
- Product Name:(1S,2R)-2-(chloromethyl)-N,N-diethyl-1- phenylcyclopropanecarboxamide
- CAS Number:1237261-60-7
- Molecular formula:C15H20ClNO
- Molecular Weight:265.78
![Cyclopropanecarboxamide,N,N-diethyl-2-(hydroxymethyl)-1-phenyl-,(1S,2R)-](/CAS/20180703/GIF/172015-99-5.gif)
172015-99-5
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![(1S,2R)-2-(chloromethyl)-N,N-diethyl-1-
phenylcyclopropanecarboxamide](/CAS/20180703/GIF/1237261-60-7.gif)
1237261-60-7
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Yield:-
Reaction Conditions:
with thionyl chloride in toluene at 25; for 1 h;Industry scale;
Steps:
step 6
24.7 kg of thionyl chloride (207 moles) are poured on the concentrate within 1 hour at 25°C under intense stirring. The reaction medium is concentrated in vacuo by limiting the temperature to 500C. This concentration operation is repeated twice after adding twice 62 L of toluene, in order to obtain a concentrate of chlorinated amide.
References:
WO2010/86394,2010,A1 Location in patent:Page/Page column 15
![Benzeneacetonitrile](/CAS/GIF/140-29-4.gif)
140-29-4
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$21.00/25mL
![(1S,2R)-2-(chloromethyl)-N,N-diethyl-1-
phenylcyclopropanecarboxamide](/CAS/20180703/GIF/1237261-60-7.gif)
1237261-60-7
7 suppliers
inquiry