ChemicalBook CAS DataBase List 1-Hydroxy-6-phenyl-4-trifluoroMethyl-1H-indole-2-carboxylic acid

1-Hydroxy-6-phenyl-4-trifluoroMethyl-1H-indole-2-carboxylic acid synthesis

4synthesis methods

Product Name:1-Hydroxy-6-phenyl-4-trifluoroMethyl-1H-indole-2-carboxylic acid
CAS Number:1269802-68-7
Molecular formula:C16H10F3NO3
Molecular Weight:321.25

1269802-97-2
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1-Hydroxy-6-phenyl-4-trifluoroMethyl-1H-indole-2-carboxylic acid

1269802-68-7
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Yield:1269802-68-7 94%

Reaction Conditions:

with lithium hydroxide in tetrahydrofuran;methanol;water at 20;

References:

Granchi, Carlotta;Roy, Sarabindu;Giacomelli, Chiara;MacChia, Marco;Tuccinardi, Tiziano;Martinelli, Adriano;Lanza, Mario;Betti, Laura;Giannaccini, Gino;Lucacchini, Antonio;Funel, Nicola;León, Leticia G.;Giovannetti, Elisa;Peters, Godefridus J.;Palchaudhuri, Rahul;Calvaresi, Emilia C.;Hergenrother, Paul J.;Minutolo, Filippo [Journal of Medicinal Chemistry,2011,vol. 54,# 6,p. 1599 - 1612] Location in patent:experimental part

5-Iodo-2-Methyl-1-nitro-3-trifluoroMethyl-benzene

259667-65-7
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1269802-68-7
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References

98-80-6 Synthesis

98-80-6
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1269802-68-7
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References

3839-29-0
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1269802-68-7
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References