![](/CAS/GIF/127199-27-3.gif)
3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo- synthesis
- Product Name:3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-
- CAS Number:127199-27-3
- Molecular formula:C13H7ClF3NO3
- Molecular Weight:317.65
![ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE](/CAS/GIF/101987-86-4.gif)
101987-86-4
143 suppliers
$6.00/1g
![3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-](/CAS/GIF/127199-27-3.gif)
127199-27-3
71 suppliers
$50.00/50mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: acetic anhydride / 1.5 h / 110 - 120 °C
1.2: 1 h / 20 °C
2.1: sodium hydride / 1,4-dioxane / 1 h
3.1: hydrogenchloride; acetic acid / water / 120 - 130 °C
References:
Liu, Yu;Liu, Lianxin;Shi, Guangxia [Asian Journal of Chemistry,2014,vol. 26,# 20,p. 7049 - 7051]
![3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-,ethyl ester](/CAS/20180703/GIF/127199-25-1.gif)
127199-25-1
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inquiry
![3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-](/CAS/GIF/127199-27-3.gif)
127199-27-3
71 suppliers
$50.00/50mg