3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo- synthesis
- Product Name:3-Quinolinecarboxylic acid, 8-chloro-6,7-difluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-
- CAS Number:127199-27-3
- Molecular formula:C13H7ClF3NO3
- Molecular Weight:317.65
101987-86-4
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127199-27-3
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Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: acetic anhydride / 1.5 h / 110 - 120 °C
1.2: 1 h / 20 °C
2.1: sodium hydride / 1,4-dioxane / 1 h
3.1: hydrogenchloride; acetic acid / water / 120 - 130 °C
References:
Liu, Yu;Liu, Lianxin;Shi, Guangxia [Asian Journal of Chemistry,2014,vol. 26,# 20,p. 7049 - 7051]
127199-25-1
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127199-27-3
71 suppliers
$50.00/50mg