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(E)-3-(3-cyclopentyloxy-4-methoxyphenyl)-2-propenoic acid synthesis

5synthesis methods
621-59-0 Synthesis
Isovanillin

621-59-0
618 suppliers
$9.00/1g

(E)-3-(3-cyclopentyloxy-4-methoxyphenyl)-2-propenoic acid

133332-31-7
1 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: 81 percent / potassium carbonate / acetone / 96 h / Heating
2.1: sodium hydride; ethyl phosphate / 1,2-dimethoxy-ethane / 4 h / 20 °C
2.2: 91 percent / 1,2-dimethoxy-ethane / 24 h / 20 °C

References:

Itoh, Kennosuke;Kanemasa, Shuji [Journal of the American Chemical Society,2002,vol. 124,# 45,p. 13394 - 13395]