ChemicalBook CAS DataBase List benzaMide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoroMethoxy)-3-hydroxy-

benzaMide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoroMethoxy)-3-hydroxy- synthesis

4synthesis methods

Product Name:benzaMide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoroMethoxy)-3-hydroxy-
CAS Number:1391052-76-8
Molecular formula:C13H8Cl2F2N2O3
Molecular Weight:349.12

151103-08-1
272 suppliers
$8.00/250mg

benzaMide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoroMethoxy)-3-hydroxy-

1391052-76-8
64 suppliers
$132.00/1mg

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: aminosulfonic acid; sodium chlorite / acetonitrile; water / 0 - 30 °C
2.1: N,N-dimethyl-formamide; thionyl chloride / toluene / 3 h / 90 °C / Reflux
3.1: sodium hydride / acetonitrile / 2 h / 0 - 5 °C
3.2: 1.5 h / 0 - 15 °C

References:

Lin, Yan;Huang, Peijun;Qi, Haofei;Chen, Ligong;Wang, Donghua [Research on Chemical Intermediates,2013,vol. 39,# 7,p. 3111 - 3115]

22889-78-7 Synthesis