ETHYL 2-CHLORO-2-[2-(4-TERT-BUTYLPHENYL)HYDRAZONO] ACETATE synthesis
1synthesis methods
- Product Name:ETHYL 2-CHLORO-2-[2-(4-TERT-BUTYLPHENYL)HYDRAZONO] ACETATE
- CAS Number:148367-96-8
- Molecular formula:C14H19ClN2O2
- Molecular Weight:282.77
Yield:148367-96-8 76%
Reaction Conditions:
Stage #1: 4-tert-Butylanilinewith hydrogenchloride;sodium nitrite in water at 5;
Stage #2: ethyl 2-chloro-3-oxo-butyrate in water at 1 - 20;
References:
Peng, Youyi;Zhang, Qiang;Arora, Sonia;Keenan, Susan M.;Kortagere, Sandhya;Wannemacher, Kenneth M.;Howells, Richard D.;Welsh, William J. [Bioorganic and Medicinal Chemistry,2009,vol. 17,# 17,p. 6442 - 6450] Location in patent:experimental part