![](/CAS/GIF/154748-63-7.gif)
Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI) synthesis
- Product Name:Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI)
- CAS Number:154748-63-7
- Molecular formula:C9H17NO3
- Molecular Weight:187.24
![3-Oxocyclobutanecarboxylic acid](/CAS/GIF/23761-23-1.gif)
23761-23-1
456 suppliers
$6.00/1g
![Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/154748-63-7.gif)
154748-63-7
101 suppliers
$10.00/250mg
Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: thionyl chloride / dichloromethane / 1.5 h / 0 °C / Reflux
2.1: sodium azide / acetone; water / 1 h / 0 °C
3.1: toluene / 90 °C
3.2: 90 °C
4.1: sodium tetrahydroborate / ethanol / 0.5 h / 0 - 20 °C
References:
AGIOS PHARMACEUTICALS, INC.;LEMIEUX, Rene M.;POPOVICI-MULLER, Janeta;TRAVINS, Jeremy;CAI, Zhenwei;CUI, Dawei;ZHOU, Ding WO2013/107291, 2013, A1
![tert-butyl 3-(benzyloxy)cyclobutylcarbamate](/CAS/20180808/GIF/154748-62-6.gif)
154748-62-6
5 suppliers
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![Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/154748-63-7.gif)
154748-63-7
101 suppliers
$10.00/250mg
![(1r,3r)-3-((tert-butoxycarbonyl)amino)cyclobutyl 4-nitrobenzoate](/CAS/20200119/GIF/871014-16-3.gif)
871014-16-3
1 suppliers
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154748-63-7
101 suppliers
$10.00/250mg
![Carbamic acid, (3-methylenecyclobutyl)-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/130369-04-9.gif)
130369-04-9
58 suppliers
$49.47/250mgs:
![Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/154748-63-7.gif)
154748-63-7
101 suppliers
$10.00/250mg
![(CIS) TERT-BUTYL-3-HYDROXYCYCLOBUTYL CARBAMATE](/CAS/GIF/389890-43-1.gif)
389890-43-1
115 suppliers
$60.00/1g
![Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/154748-63-7.gif)
154748-63-7
101 suppliers
$10.00/250mg