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ChemicalBook CAS DataBase List 3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one
158299-05-9

3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 92 percent / p-toluenesulfonic acid monohydrate / toluene / 8 h / Heating
2: 87 percent / pyridine / toluene / 1) 5-15 deg C, 30 min; 2) 25 deg C, 17 h

References:

Kondo;Seki;Kuroda;Yamanaka;Iwasaki [Journal of Organic Chemistry,1997,vol. 62,# 9,p. 2877 - 2884]

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