ChemicalBook CAS DataBase List 3-De[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-11-deoxy-6-O-methyl-3-oxo-erythromycin 2'-acetate

3-De[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-11-deoxy-6-O-methyl-3-oxo-erythromycin 2'-acetate synthesis

5synthesis methods

Product Name:3-De[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-11-deoxy-6-O-methyl-3-oxo-erythromycin 2'-acetate
CAS Number:160145-82-4
Molecular formula:C32H53NO10
Molecular Weight:611.76

Erythromycin, 3-O-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)-6-O-methyl-, 2'-acetate

143353-81-5
0 suppliers
inquiry

3-De[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-11-deoxy-6-O-methyl-3-oxo-erythromycin 2'-acetate

160145-82-4
15 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 3 steps
1: pyridine / dichloromethane / 23 h / 0 - 20 °C
2: N-chloro-succinimide; thioformaldehyde / dichloromethane / 3.5 h / -5 °C
3: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetone / 14 h / Reflux

References:

Wei, Xin;You, Qidong [Organic Process Research and Development,2006,vol. 10,# 3,p. 446 - 449]