3-Furanpropanoyl chloride, 2,5-dihydro-4-methyl-2,5-dioxo- synthesis

10synthesis methods

Product Name:3-Furanpropanoyl chloride, 2,5-dihydro-4-methyl-2,5-dioxo-
CAS Number:160239-81-6
Molecular formula:C8H7ClO4
Molecular Weight:202.59

487-66-1 Synthesis

2,5-Dihydro-4-methyl-2,5-dioxo-3-furanpropanoic Acid

487-66-1
33 suppliers
$38.00/250mg

3-Furanpropanoyl chloride, 2,5-dihydro-4-methyl-2,5-dioxo-

160239-81-6
0 suppliers
inquiry

Yield:160239-81-6 97%

Reaction Conditions:

with oxalyl dichloride;N,N-dimethyl-formamide in dichloromethane at 25; for 1 h;

Steps:

1

CDM (1.840 g, 0.010 mol) was completely dissolved in anhydrous dichloromethane (20 mE) at 0° C., N,N-dimethylformamide (50 jt) and oxalyl dichloride (3.8 10 g, 0.030 mol) were successively added. After kept for 10 mm, reaction was continued at 25° C. for 1 h. Dichloromethane was removed with a rotary evaporator, and N,N-dimethylformamide was removed by distillation under 15.0 Pa to obtain an intermediate, acyl-chlorinated CDM (1.96 g, with a yield of 97%).

References:

US2019/60463,2019,A1 Location in patent:Paragraph 0170

13192-04-6
170 suppliers
$11.00/1g

160239-81-6
0 suppliers
inquiry

References

766-39-2 Synthesis

766-39-2
237 suppliers
$10.00/5g

160239-81-6
0 suppliers
inquiry

References

98453-81-7
21 suppliers
inquiry

160239-81-6
0 suppliers
inquiry

References

Propanedioic acid, 2-[(2,5-dihydro-4-methyl-2,5-dioxo-3-furanyl)methyl]-, 1,3-diethyl ester

347406-12-6
0 suppliers
inquiry

160239-81-6
0 suppliers
inquiry

References