ChemicalBook CAS DataBase List 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid

5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid synthesis

4synthesis methods

Product Name:5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid
CAS Number:160384-40-7
Molecular formula:C21H21ClN4O4S
Molecular Weight:460.93

19398-61-9 Synthesis

19398-61-9
114 suppliers
$10.00/5G

5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid

160384-40-7
10 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 6 steps
1: 56 percent / conc. H₂SO₄, HNO₃ / acetic acid / 2 h / Ambient temperature
2: 58 percent / tetrahydrofuran / 8 h / Heating
3: 93 percent / acetic acid / Ambient temperature
4: 71 percent / acetic acid, sodium triacetoxyborohydride / 1,2-dichloro-ethane
5: 82.5 percent / potassium hydroxide / various solvent(s) / 4 h / 57 °C / solvent: N-methyl-pyrrolidinone
6: aq. HCl

References:

Urban, Frank J.;Breitenbach, Ralph;Gonyaw, Dianne [Synthetic Communications,1996,vol. 26,# 8,p. 1629 - 1638]

160384-39-4 Synthesis

2-[5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitrophenyl]-propanedioic Acid 1,3-DiMethyl Ester

160384-39-4
10 suppliers
inquiry

160384-40-7
10 suppliers
inquiry

References

7149-76-0 Synthesis

7149-76-0
10 suppliers
$28.60/50MG

160384-40-7
10 suppliers
inquiry

References

3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethyl]-1-piperazinyl]-1,2-benzisothiazole

160384-38-3
11 suppliers
inquiry

160384-40-7
10 suppliers
inquiry

References

5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid Related Search:

3-(1-Piperazinyl)-1,2-benzisothiazole