ChemicalBook CAS DataBase List Benzofuro[2,3-b]pyridine, 2-(methyl-d3)-8-(2-pyridinyl)-

Benzofuro[2,3-b]pyridine, 2-(methyl-d3)-8-(2-pyridinyl)- synthesis

8synthesis methods

Product Name:Benzofuro[2,3-b]pyridine, 2-(methyl-d3)-8-(2-pyridinyl)-
CAS Number:1609374-00-6
Molecular formula:C17H12N2O
Molecular Weight:260.3

1609373-99-0 Synthesis

2-Methyl-8-(pyridin-2-yl)benzofuro[2,3-b]pyridine

1609373-99-0
78 suppliers
inquiry

Benzofuro[2,3-b]pyridine, 2-(methyl-d3)-8-(2-pyridinyl)-

1609374-00-6
15 suppliers
inquiry

Yield:1609374-00-6 85%

Reaction Conditions:

with sodium methylate in ethyl [2]alcohol; for 60 h;Inert atmosphere;Reflux;

Steps:

5 Example 5 Preparation of the iridium complex AG019 of the present invention

Preparation of the main ligand L5-3: Under a nitrogen atmosphere, add L4-2 (6.15 mmol), sodium ethoxide (12.3 mmol), and ethanol-d1 (25 ml) into the flask, and stir at reflux for 60 hours. After the reaction is completed, the solvent is removed by spinning off, appropriate water and ethyl acetate are added, the layers are separated, the organic phase is dried, and the product is separated by 200-300 mesh silica gel column chromatography to obtain a white solid product of 5.22 mmol, with a yield of 85%.

References:

CN113121606,2021,A Location in patent:Paragraph 0057-0059

1609373-98-9 Synthesis

2-Methylbenzofuro[2,3-b]pyridin-8-yl trifluoromethanesulfonate

1609373-98-9
73 suppliers
inquiry

1609374-00-6
15 suppliers
inquiry

References

40972-86-9
231 suppliers
$10.00/1g

1609374-00-6
15 suppliers
inquiry

References

126325-46-0
231 suppliers
$10.00/250mg

1609374-00-6
15 suppliers
inquiry

References

2-Pyridinamine, 3-(2,3-dimethoxyphenyl)-6-methyl-

1609373-95-6
0 suppliers
inquiry

1609374-00-6
15 suppliers
inquiry

References