TERT-BUTYL 4-CYANO-4-(PYRIDIN-2-YL)PIPERIDINE-1-CARBOXYLATE synthesis
3synthesis methods
- Product Name:TERT-BUTYL 4-CYANO-4-(PYRIDIN-2-YL)PIPERIDINE-1-CARBOXYLATE
- CAS Number:167263-04-9
- Molecular formula:C16H21N3O2
- Molecular Weight:287.36
Yield:167263-04-9 89%
Reaction Conditions:
with lithium hexamethyldisilazane in tetrahydrofuran at -78 - 20;Inert atmosphere;
References:
Chang, Ronald K.;Di Marco, Christina N.;Pitts, Daniel R.;Greshock, Thomas J.;Kuduk, Scott D. [Tetrahedron Letters,2009,vol. 50,# 46,p. 6303 - 6306] Location in patent:experimental part