Ketoconazole Impurity 9 (Ketoconazole Hydroxymethyl Impurity) synthesis
- Product Name:Ketoconazole Impurity 9 (Ketoconazole Hydroxymethyl Impurity)
- CAS Number:170210-42-1
- Molecular formula:C14H14Cl2N2O3
- Molecular Weight:329.18
65277-42-1
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Yield:-
Reaction Conditions:
with mutant of unspecific peroxygenase from agrocybe aegerita;oxalate oxidase from Hordeum vulgare(barley) in aq. buffer at 25; pH=4; for 24 h;Enzymatic reaction;
References:
Romero, Elvira;Johansson, Magnus J.;Cartwright, Jared;Grogan, Gideon;Hayes, Martin A. [Angewandte Chemie - International Edition,2022,vol. 61,# 39,art. no. E202207831][Angew. Chem.,2022,vol. 134,# 39] Location in patent:supporting information