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1-[1-(4-fluorobenzyl)piperidin-4-yl]methanamine(SALTDATA: FREE) synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / methanol / 5 h / 85 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 75 °C / Inert atmosphere

References:

Mo, Jun;Chen, Tingkai;Yang, Hongyu;Guo, Yan;Li, Qi;Qiao, Yuting;Lin, Hongzhi;Feng, Feng;Liu, Wenyuan;Chen, Yao;Liu, Zongliang;Sun, Haopeng [Journal of Enzyme Inhibition and Medicinal Chemistry,2020,vol. 35,# 1,p. 330 - 343]