ChemicalBook CAS DataBase List 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)

1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) synthesis

4synthesis methods

Product Name:1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)
CAS Number:190141-99-2
Molecular formula:C9H18N2O3
Molecular Weight:202.25

114214-49-2
183 suppliers
$9.00/1g

1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI)

190141-99-2
69 suppliers
$17.00/100mg

Yield:190141-99-2 100%

Reaction Conditions:

with ammonia in water at 70;Sealed tube;

Steps:

3.1 Step 1) 3-Amino-4-hydroxy-tetrahydropyrrole-1-carboxylic acid tert-butyl ester 3b

Ammonia water (66mL, 33%wt) was added to 3-N-tert-butoxycarbonyl-6-oxa-3-azabicyclo[3.1.0]hexane 3a (10.0g, 54.0mmol) at 70°CSealing reaction. The reaction solution was concentrated to obtain the title compound 3b (10.9 g, yield 100%) as a yellow viscous material.

References:

CN111196806,2020,A Location in patent:Paragraph 0307; 0309-0312

tert-butyl 3-azido-4-hydroxypyrrolidine-1-carboxylate

203434-45-1
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inquiry

190141-99-2
69 suppliers
$17.00/100mg

References

73286-70-1 Synthesis

73286-70-1
292 suppliers
$6.00/5g

190141-99-2
69 suppliers
$17.00/100mg

References

24424-99-5 Synthesis

24424-99-5
821 suppliers
$13.50/25G

190141-99-2
69 suppliers
$17.00/100mg

References

1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester(9CI) Related Search:

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