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ChemicalBook CAS DataBase List 1H-Indole-7-carboxaldehyde, 1-methyl- (9CI)
69047-36-5

1H-Indole-7-carboxaldehyde, 1-methyl- (9CI) synthesis

8synthesis methods
-

Yield:69047-36-5 96%

Reaction Conditions:

Stage #1: 1H-indole-7-carbaldehydewith sodium hydride in tetrahydrofuran;mineral oil at 0; for 0.5 h;Inert atmosphere;
Stage #2: methylene chloride in tetrahydrofuran;mineral oil at 0 - 20;Inert atmosphere;

References:

Jadhav, Pankaj P.;Kahar, Nilesh M.;Dawande, Sudam G. [Organic Letters,2021,vol. 23,# 22,p. 8673 - 8677] Location in patent:supporting information