ChemicalBook CAS DataBase List (1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL

(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL synthesis

3synthesis methods

Product Name:(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL
CAS Number:849067-97-6
Molecular formula:C8H8N2O
Molecular Weight:148.16

849067-90-9 Synthesis

849067-90-9
96 suppliers
$85.00/250mg

(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL

849067-97-6
64 suppliers
$65.00/50mg

Yield: 76%

Reaction Conditions:

with methanol;sodium tetrahydroborate for 1 h;

Steps:

93
To the solution of lH-pyrrolo[2,3-b]pyridine-5-carbaldehyde (400 mg, 2.73 mmol, 1.0 eq) in MeOH (10 mL) was added sodium borohydride (208 mg, 5.46 mmol, 2.0 eq). The reaction was stirred for 1 h, and then purified via flash chromatography to afford (lH-pyrrolo[2,3-b]pyridin-5-yl)methanol as a white solid (310 mg, 76%).

References:

LIFESCI PHARMACEUTICALS, INC.;MCDONALD, Andrew WO2015/103317, 2015, A1 Location in patent:Page/Page column 175

849067-96-5 Synthesis

1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER

849067-96-5
109 suppliers
$23.00/250mg

849067-97-6
64 suppliers
$65.00/50mg

References

754214-42-1 Synthesis

1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID

754214-42-1
141 suppliers
$20.00/100mg

849067-97-6
64 suppliers
$65.00/50mg

References

(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-METHANOL Related Search:

1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID (5-METHOXY-1H-PYRROLO[2,3-C]PYRIDIN-2-YL)METHANOL 3-IODO-1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLICACIDMETHYLESTER 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 6-methyl- 1H-PYRROLO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER