![](/CAS/GIF/1279032-31-3.gif)
(1R,3S)-3-AMinocyclopentanol hydrochloride synthesis
- Product Name:(1R,3S)-3-AMinocyclopentanol hydrochloride
- CAS Number:1279032-31-3
- Molecular formula:C5H12ClNO
- Molecular Weight:137.61
![Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/167465-99-8.gif)
167465-99-8
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$35.00/100mg
![(1R,3S)-3-AMinocyclopentanol hydrochloride](/CAS/GIF/1279032-31-3.gif)
1279032-31-3
163 suppliers
$39.00/100mg
Yield:1279032-31-3 95%
Reaction Conditions:
with hydrogenchloride in 1,4-dioxane at 20; for 2 h;
Steps:
4 Example 4:Compounds of formula V undergo a de Boc reaction to form a salt to give a compound of formula VI
10 g of the compound of formula V is dissolved in 20 mL of dioxane,Add 50 mL of dioxane hydrochloride (4M) and stir at room temperature for 2 h. Spin the reaction solution,100 mL of acetonitrile was beaten, suction filtered, and the filter cake was rinsed with 100 mL of acetonitrile.Dry blast to give 6.4 g of a white solid.The yield was 95%.
References:
Changzhou Pharmaceutical Factory Co., Ltd.;Sun Guangxiang;Zhang Yunran;Sun Haijiang;Wang Minfeng;Tao Weijie;Fu Jun;Ma Xuwei;Li Xingang CN109020911, 2018, A Location in patent:Paragraph 0085; 0086; 0087; 0088; 0089; 0090
![(1R,3S)-3-Aminocyclopentanol](/CAS/GIF/1110772-05-8.gif)
1110772-05-8
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$25.00/10 mg
![(1R,3S)-3-AMinocyclopentanol hydrochloride](/CAS/GIF/1279032-31-3.gif)
1279032-31-3
163 suppliers
$39.00/100mg
![1,3-Cyclopentadiene](/CAS/GIF/542-92-7.gif)
542-92-7
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![(1R,3S)-3-AMinocyclopentanol hydrochloride](/CAS/GIF/1279032-31-3.gif)
1279032-31-3
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$39.00/100mg
![Ethanone, 2-hydroxy-1-(1S,4R)-2-oxa-3-azabicyclo[2.2.1]hept-5-en-3-yl-2-phenyl-, (2R)-](/CAS/20200611/GIF/126924-22-9.gif)
126924-22-9
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![(1R,3S)-3-AMinocyclopentanol hydrochloride](/CAS/GIF/1279032-31-3.gif)
1279032-31-3
163 suppliers
$39.00/100mg