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2-(1H-BENZIMIDAZOL-1-YL)PROPANOIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydride / N,N-dimethyl-formamide; paraffin oil / 3 h / 20 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / ethanol / 24 h / 20 °C / 760.05 Torr / Inert atmosphere

References:

Tokumaru, Eri;Tengeiji, Atsushi;Nakahara, Takayoshi;Shiina, Isamu [Chemistry Letters,2015,vol. 44,# 12,p. 1768 - 1770]