2,2,2-trifluoro-1-(2-fluorophenyl)ethanol synthesis
- Product Name:2,2,2-trifluoro-1-(2-fluorophenyl)ethanol
- CAS Number:124004-74-6
- Molecular formula:C8H6F4O
- Molecular Weight:194.13
81290-20-2
410 suppliers
$13.00/1g
446-52-6
423 suppliers
$6.00/25g
124004-74-6
18 suppliers
$220.00/50mg
Yield:124004-74-6 77%
Reaction Conditions:
Stage #1: (trifluoromethyl)trimethylsilane;2-Fluorobenzaldehyde in tetrahydrofuran at 0; for 0.166667 h;Inert atmosphere;Sealed tube;
Stage #2: with tetrabutyl ammonium fluoride in tetrahydrofuran at 0 - 20;Inert atmosphere;Sealed tube;
Stage #3: with tetrabutyl ammonium fluoride;water in tetrahydrofuran at 0 - 20;Inert atmosphere;Sealed tube;
References:
Kelly, Christopher B.;Mercadante, Michael A.;Hamlin, Trevor A.;Fletcher, Madison H.;Leadbeater, Nicholas E. [Journal of Organic Chemistry,2012,vol. 77,# 18,p. 8131 - 8141]
124004-75-7
51 suppliers
$45.00/10mg
124004-74-6
18 suppliers
$220.00/50mg