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ChemicalBook CAS DataBase List (2,2-dimethylpropyl)ethylamine(SALTDATA: HCl)

(2,2-dimethylpropyl)ethylamine(SALTDATA: HCl) synthesis

5synthesis methods
-

Yield:17839-28-0 98%

Reaction Conditions:

with triethylamine

Steps:

(2,2-Dimethyl-propyl)-ethyl-amine

(2,2-Dimethyl-propyl)-ethyl-amine A solution of neopentylamine (2.0 g, 23.0 mmol), acetyl chloride (1.96 mL, 27.6 mmol), triethylamine (3.84 mL, 27.5 mmol), and DCM (100 mL) were stirred at room temp for 2 h. The mixture was poured into water and extracted with DCM (3*40 mL). The organic phase was dried over Na2SO4, and the solvent was removed to afford N-neopentylacetamide as white solid (2.90 g, 98%). NMR confirmed the structure of N-neopentylacetamide.

References:

US2002/65270,2002,A1