2,3,4,6-TETRAFLUOROBENZOYL CHLORIDE synthesis
- Product Name:2,3,4,6-TETRAFLUOROBENZOYL CHLORIDE
- CAS Number:123016-51-3
- Molecular formula:C7HClF4O
- Molecular Weight:212.53
32890-92-9
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$50.00/250mg
123016-51-3
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$64.70/5g
Yield:123016-51-3 99%
Reaction Conditions:
with thionyl chloride in N,N-dimethyl-formamide at 70;
Steps:
3 Example 3 Synthesis of 2,4,5,6-tetrafluorobenzyl alcohol
50 g (0.258 mol) of 2,4,5,6-tetrafluorobenzoic acid was added to 150 mL of thionyl chloride, 3 drops of DMF were added dropwise, and the temperature was raised to 70 ° C to carry out a reflux reaction. When the solution became clear, no gas was discharged. The time is considered to be the end of the reaction. The thionyl chloride was recovered by atmospheric distillation, and then distilled under reduced pressure to give 2,4,5,6-tetrafluorobenzoyl chloride 54.1 as a colorless oil, yield 99%
References:
CN109293478,2019,A Location in patent:Paragraph 0052; 0053
1551-39-9
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$23.00/100mg
123016-51-3
16 suppliers
$64.70/5g