2,3,4-Trihydroxybenzaldehyde synthesis
- Product Name:2,3,4-Trihydroxybenzaldehyde
- CAS Number:2144-08-3
- Molecular formula:C7H6O4
- Molecular Weight:154.12
This method takes pyrogallol as an initial raw material. It comprises three steps of phenolic hydroxyl protection, formylation, and deprotection: protecting two adjacent phenolic hydroxyl groups in the pyrogallol to obtain 4-hydroxybenzo[d][1,3]dioxol-2-one, then performing formylation to obtain 7-hydroxy-2-oxobenzo[d][1,3]dioxole-4-carbaldehyde, and finally removing a protecting group to get a target 2,3,4-trihydroxybenzaldehyde.
102-09-0
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2144-08-3
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$5.00/1g
Yield:-
Steps:
Multi-step reaction with 3 steps
1: triethylamine / tert-butyl methyl ether / Reflux
2: aluminum (III) chloride / tert-butyl methyl ether / 0 - 5 °C
3: water / Reflux
References:
CN112830872,2021,A
141-78-6
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87-66-1
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2144-08-3
331 suppliers
$5.00/1g
