2,3,4-Trihydroxybenzaldehyde
- CAS No.
- 2144-08-3
- Chemical Name:
- 2,3,4-Trihydroxybenzaldehyde
- Synonyms
- 2,3,4-Trihydroxybenazldehyde;NSC 22595;2,3,4-THB;PYROGALLOLALDEHYDE;2,3,4-TrihydroxybenzaL;Pyrogallolcarboxaldehyde;,3,4-Trihydroxybenzaldehyd;PYROGALLOL-4-CARBOXALDEHYDE;2,3,4-Trihdroxybenzaldehyde;2,3,4-TRIHYDROXYBENZALDEHYDE
- CBNumber:
- CB1396755
- Molecular Formula:
- C7H6O4
- Molecular Weight:
- 154.12
- MDL Number:
- MFCD00003325
- MOL File:
- 2144-08-3.mol
- MSDS File:
- SDS
| Melting point | 159-161 °C (lit.) |
|---|---|
| Boiling point | 237.46°C (rough estimate) |
| Density | 1.3725 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO, Methanol |
| pka | 7.41±0.23(Predicted) |
| form | Powder |
| color | Light brown to beige-brown |
| Water Solubility | 1.541g/L at 25℃ |
| Sensitive | Air Sensitive |
| BRN | 2328658 |
| LogP | 1.25 |
| CAS DataBase Reference | 2144-08-3(CAS DataBase Reference) |
| FDA UNII | 7UGV46Q4M2 |
| EPA Substance Registry System | Benzaldehyde, 2,3,4-trihydroxy- (2144-08-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CU8439800 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29124990 | |||||||||
| NFPA 704 |
|
2,3,4-Trihydroxybenzaldehyde price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 260843 | 2,3,4-Trihydroxybenzaldehyde 98% | 2144-08-3 | 5g | $67.2 | 2024-03-01 | Buy |
| TCI Chemical | T2158 | 2,3,4-Trihydroxybenzaldehyde >98.0%(GC)(T) | 2144-08-3 | 5g | $30 | 2024-03-01 | Buy |
| TCI Chemical | T2158 | 2,3,4-Trihydroxybenzaldehyde >98.0%(GC)(T) | 2144-08-3 | 25g | $87 | 2024-03-01 | Buy |
| Alfa Aesar | A13745 | 2,3,4-Trihydroxybenzaldehyde, 98% | 2144-08-3 | 5g | $42.65 | 2024-03-01 | Buy |
| Alfa Aesar | A13745 | 2,3,4-Trihydroxybenzaldehyde, 98% | 2144-08-3 | 25g | $177 | 2024-03-01 | Buy |
2,3,4-Trihydroxybenzaldehyde Chemical Properties,Uses,Production
Description
2,3, 4-trihydroxybenzaldehyde is an essential intermediate of the antiparkinson drug benserazide, which is a peripheral dopa decarboxylase inhibitor, usually benserazide: the L-dopa is prepared into a compound preparation at a ratio of 1:4, and has a remarkable effect of treating the Parkinson's disease.
Chemical Properties
light brown to beige-brown powder
Uses
2,3,4-Trihydroxybenzaldehyde has been used in the preparation of 1,5-dimethyl-2-phenyl-4-[(1E)-(2,3,4-trihydroxybenzylidene)amino]-1H-pyrazol-3(2H)-one.
Uses
2,3,4-Trihydroxybenzaldehyde is a phenolic benzaldehyde with antibacterial activity.
General Description
Antimicrobial activity of carbohydrazone derived from 2,3,4-trihydroxybenzaldehyde against bacteria and fungi has been investigated. 2,3,4-trihydroxybenzaldehyde forms Schiff bases via [1+1] condensation with anthranilic acid.
Synthesis
The method for synthesizing 2,3, 4-trihydroxybenzaldehyde is shown as follows. 
This method takes pyrogallol as an initial raw material. It comprises three steps of phenolic hydroxyl protection, formylation, and deprotection: protecting two adjacent phenolic hydroxyl groups in the pyrogallol to obtain 4-hydroxybenzo[d][1,3]dioxol-2-one, then performing formylation to obtain 7-hydroxy-2-oxobenzo[d][1,3]dioxole-4-carbaldehyde, and finally removing a protecting group to get a target 2,3,4-trihydroxybenzaldehyde.
2,3,4-Trihydroxybenzaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiurui Biology Chemistry Co.,Ltd. | +86-0744-8561603 +8619974416182 | sales11@jiuruibiochem.com | China | 26 | 58 |
| Hangzhou Benoy Chemical Co., Ltd | +8617342059697 | sales@benoychem.com | China | 315 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| Zhejiang Brunova Technology Co., Ltd. | 8617857108485 17857108485 | info@zjbrunova.com | China | 48 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5854 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18137 | 58 |
| Fuzhou Lista Biotechnology Co.,Ltd | sallychris2021@gmail.com | China | 98 | 58 | |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 | admin@86-ss.com | China | 1001 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | info@dakenam.com | China | 19788 | 58 |
Related articles
- 2,3,4-Trihydroxybenzaldehyde: the potential for anti-obesity
- 2,3,4-Trihydroxy-benzaldehyde, C7H6O4, crystallizes with two independent mol-ecules in the asymmetric unit.
- Mar 27，2025
View Lastest Price from 2,3,4-Trihydroxybenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-16 | 2,3,4-Trihydroxybenzaldehyde
2144-08-3
|
US $0.00 / kg | 1kg | 99.5%min | 2000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-04-16 | 2,3,4-Trihydroxybenzaldehyde
2144-08-3
|
US $0.00-0.00 / kg | 1kg | 98 | 1000 | Wuhan Circle Star Chem-medical Technology Co.,Ltd | |
 |
2025-04-16 | 2,3,4-Trihydroxybenzaldehyde
2144-08-3
|
US $990.00-800.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD |
-
- 2,3,4-Trihydroxybenzaldehyde
2144-08-3
- US $0.00 / kg
- 99.5%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2,3,4-Trihydroxybenzaldehyde
2144-08-3
- US $0.00-0.00 / kg
- 98
- Wuhan Circle Star Chem-medical Technology Co.,Ltd
-
- 2,3,4-Trihydroxybenzaldehyde
2144-08-3
- US $990.00-800.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
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