ChemicalBook CAS DataBase List 2,3-Dihydro-5-methyl-4H-1-benzopyran-4-one

2,3-Dihydro-5-methyl-4H-1-benzopyran-4-one synthesis

5synthesis methods

Product Name:2,3-Dihydro-5-methyl-4H-1-benzopyran-4-one
CAS Number:18385-68-7
Molecular formula:C10H10O2
Molecular Weight:162.19

25173-36-8
38 suppliers
$50.00/500mg

18385-69-8 Synthesis

7-Methyl-2,3-dihydro-4H-1-benzopyran-4-one

18385-69-8
37 suppliers
$107.00/100mg

2,3-Dihydro-5-methyl-4H-1-benzopyran-4-one

18385-68-7
36 suppliers
$100.00/50mg

Yield:18385-68-7 45% ，18385-69-8 55%

Reaction Conditions:

with acid activated montmorillonite K-10 in toluene; for 0.5 h;Reflux;Inert atmosphere;

Steps:

General experimental procedure for the synthesis of chroman-4-one (4a-4p)

General procedure: A mixture of 3-aryloxypropionic acid 3a-3o (1.0 mmol) and freshly prepared AA.Mont.K-10 (300% by weight) in toluene (2 mL) was heated to reflux under inert atmosphere for the specified time (30-45 minutes). After reaction completion, reaction mixture is cooled and added CH₂Cl₂ (10-15 mL). Filtered the AA.Mont.K-10 and washed twice with CH₂Cl₂. The organic filtrate is concentrated and the crude mass is extracted with hexane (10-15 mL) to afford pure chromanones 4a-4p.

References:

Begum, Ayisha F.;Balasubramanian, Kalpattu K.;Shanmugasundaram, Bhagavathy [Tetrahedron Letters,2021,vol. 82,art. no. 153372] Location in patent:supporting information

25173-36-8
38 suppliers
$50.00/500mg

18385-68-7
36 suppliers
$100.00/50mg

References

106-44-5 Synthesis