![](/CAS/GIF/34004-36-9.gif)
(2,3-dihydroxypropyl)trimethylammonium chloride synthesis
- Product Name:(2,3-dihydroxypropyl)trimethylammonium chloride
- CAS Number:34004-36-9
- Molecular formula:C6H16ClNO2
- Molecular Weight:169.6497
![3-Chloro-1,2-propanediol](/CAS/GIF/96-24-2.gif)
96-24-2
290 suppliers
$11.00/5g
![Trimethylamine](/CAS/GIF/75-50-3.gif)
75-50-3
252 suppliers
$15.00/25ml
![(2,3-dihydroxypropyl)trimethylammonium chloride](/CAS/GIF/34004-36-9.gif)
34004-36-9
39 suppliers
$89.00/250mg
Yield: 91.2%
Reaction Conditions:
in water at 90; for 16 h;
Steps:
1 Synthesis of (±) -2,3-dihydroxypropyl trimethylammonium chloride
0.00 g of (±)-3-chloro-1,2-propanediol (0.452 mol), 178.00 g of a 30% aqueous solution of trimethylamine (0.904 mol) and 50 mL of water were added to a 500 mL vial.Then, the temperature was raised to 90 ° C, and the mixture was stirred for 16 hours to complete the reaction of the raw material 3-chloro-1,2-propanediol.The temperature was lowered to 20 ° C, and the reaction mixture was washed three times with ethyl acetate (100 mL×3), and the aqueous solution was collected and concentrated to dryness to give a white solid (70.00 g), yield 91.2%, HPLC purity 93.40%.
References:
Aisite (Chengdu) Bio-pharmaceutical Co., Ltd.;Wen Wandong;Ding Gang;Hu Zhipeng;Cheng Rui;Guo Peng CN108129338, 2018, A Location in patent:Paragraph 0027; 0029; 0030
![Glycidol](/CAS/GIF/556-52-5.gif)
556-52-5
251 suppliers
$17.67/1gm:
![Trimethylamine hydrochloride](/CAS/GIF/593-81-7.gif)
593-81-7
440 suppliers
$13.00/25g
![(2,3-dihydroxypropyl)trimethylammonium chloride](/CAS/GIF/34004-36-9.gif)
34004-36-9
39 suppliers
$89.00/250mg
![2-Chloroethanol](/CAS/GIF/107-07-3.gif)
107-07-3
3 suppliers
$18.30/50ml
![Trimethylamine](/CAS/GIF/75-50-3.gif)
75-50-3
252 suppliers
$15.00/25ml
![(2,3-dihydroxypropyl)trimethylammonium chloride](/CAS/GIF/34004-36-9.gif)
34004-36-9
39 suppliers
$89.00/250mg