2-(4-AMINOPHENYL)-6-AMINOBENZOXAZOLE synthesis
- Product Name:2-(4-AMINOPHENYL)-6-AMINOBENZOXAZOLE
- CAS Number:16363-53-4
- Molecular formula:C13H11N3O
- Molecular Weight:225.25
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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16363-53-4
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$140.00/5 g
Yield: 80%
Reaction Conditions:
with palladium on activated charcoal in tetrahydrofuran at 50; under 13446.2 Torr;
Steps:
1-3 Step 1-3: Reduction of nitro product 2
As shown in the above reaction scheme, after the product 2 was dissolved in THF,After adding the metal catalyst Pd / C into the hydrogenation tank,The hydrogenation reaction was carried out by heating and stirring at a pressure of 260 psi (the amount of the visible material was adjusted), and the hydrogenation temperature was 50 ° C.The reaction can be carried out using a TLC test piece (eluent: ethyl acetate: n-hexane = 1: 1, Rf = 0.16) to confirm whether the reaction is complete. After the reaction was complete, the Pd / C was filtered,The reaction solution was poured into 1200 ml of n-hexane to precipitate a solid. Filter to collect solids,And dried in a vacuum oven to obtain 30 g of product 3: Yield 80%.
References:
SHIFENG TECHNOLOGY CO., LTD.;LEE, CHIAHSIN;TANG, TSEMIN;CHU, LI HSIUNG;CHANG, ΗΑO PU;YANG, CHENG HSIEN TWI558696, 2016, B Location in patent:Paragraph 0028; 0033-0034
121-88-0
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16363-53-4
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$140.00/5 g
122-04-3
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16363-53-4
53 suppliers
$140.00/5 g
1000210-73-0
0 suppliers
inquiry
16363-53-4
53 suppliers
$140.00/5 g