ChemicalBook CAS DataBase List 2-(4-Bromophenyl)-5-phenylthiophene

2-(4-Bromophenyl)-5-phenylthiophene synthesis

8synthesis methods

Product Name:2-(4-Bromophenyl)-5-phenylthiophene
CAS Number:118621-30-0
Molecular formula:C16H11BrS
Molecular Weight:315.23

589-87-7 Synthesis

589-87-7
531 suppliers
$10.00/1g

306934-95-2 Synthesis

306934-95-2
80 suppliers
$10.00/100mg

118621-30-0
105 suppliers
$14.00/100mg

Yield: 83%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium⁽⁰⁾;potassium carbonate in ethanol;water;toluene at 110;Inert atmosphere;

Steps:

2.3 (3) Synthesis of Intermediate-9
20.4 g (100 mmol, 1.0 eq.) of 5-phenyl-2-thiophenolboronic acid and 31.1 g (110 mmol, 1.1 eq.) of p-bromoiodobenzene were added to a 2 L three-necked flask and 1000 ml of toluene and 100 ml of ethanol were added. Dissolve, purge with nitrogen for 15 minutes, add 150 ml of 2M aqueous solution containing 41.5 g (300 mmol, 3.0 eq.) of K2CO3, and finally add 2.3 g of Pd(PPh3)4 (2 mol%). The temperature was raised to 110°C and the reaction was completed overnight. Activated carbon adsorption was added, suction filtration, solvent removal, drying and recrystallization from toluene and ethanol gave 26.2 g of intermediate-9 with a yield of 83%.

References:

Nanjing Gao Guang Semiconductor Materials Co., Ltd.;Jin Zhenyu;Qian Chao;Wang Xiaowei;Dai Peipei CN108101896, 2018, A Location in patent:Paragraph 0082; 0091-0094; 0178

29488-24-2 Synthesis