2,4-Dihydroxy-5-nitrobenzaldehyde synthesis

4synthesis methods

Product Name:2,4-Dihydroxy-5-nitrobenzaldehyde
CAS Number:53844-98-7
Molecular formula:C7H5NO5
Molecular Weight:183.12

95-01-2
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Yield:53844-98-7 88%

Reaction Conditions:

with nitric acid;acetic acid at 20; for 2 h;Cooling with ice;

Steps:

33 2,4-hydroxy-3-nitrobenzaldehydeSynthesis of (33A)

General procedure: 2,4-Hydroxybenzaldehyde (10.0g, 72.4mmol) was dissolved in acetic acid (20mL), cooled in an ice bath, concentrated nitric acid (20mL) was added dropwise, and reacted at room temperature for 2 hours,The reaction solution was poured into 200 mL of saturated brine, filtered off with suction, and dried to obtain 11.6 g of light yellow solid with a yield of 88%.

References:

CN111187172,2020,A Location in patent:Paragraph 0230-0234

6468-19-5 Synthesis